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James N. Allen, Jr., MD Professor - Clinical Pulmonary, Allergy, Critical Care & Sleep Medicine Department of Internal Medicine College of Medicine The Ohio State University

Answers questions in the following forums:

• Lung Center
• Pulmonary Fibrosis

NetWellness Articles associated with this Author:

	Article Name	Forum
	Overview	Pulmonary Fibrosis
	What is Lung Scarring?	Lung Center

Practice Address:

Ohio State University Hospital East, Suite 1103b, Tower Building
1492 East Broad St .
Columbus, Ohio 43205
(614)-257-3044

Education:

• M.D., Ohio State University; Columbus, Ohio; 1984.
• B.A., magna cum laude; Miami University; Oxford, Ohio; 1980.

Post Graduate Training:

• Chief Residency in Internal Medicine, Ohio State University Hospitals: 1988-1989.
• Fellowship in Pulmonary and Critical Care Medicine, Ohio State University Hospitals: 1987-1991.
• Internship and Residency in Internal Medicine, Ohio State University Hospitals: 1984-1987.

Licensure or Certification:

• Diplomate of the American Board of Internal Medicine, Critical Care Mecicine, 1991 (certificate valid through 2001). Recertification, 2000 (certificate valid through 2010).
• Diplomate of the American Board of Internal Medicine, Pulmonary Disease, 1990 (certificate valid through 2000). Recertification, 2000 (certificate valid through 2010).
• Diplomate of the American Board of Internal Medicine, 1987 (lifetime certificate)
• Diplomate of the American Board of Medical Examiners, 1985

Associations:

• Society for Critical Care Medicine, 2003 - present
• Association of Professors of Medicine, 2003 - present
• American College of Physician Executives, 2001-present
• International Society of Cryosurgery, 2000-present
• National Association for the Medical Direction of Respiratory Care, 1997-present
• American College of Physicians, 1993-present.
• American Federation for Medical Research, 1991-2000
• American Thoracic Society, 1988-present.
• Ohio Thoracic Society, 1988-present.
• American College of Chest Physicians, 1986-present (FCCP 1994).

Affiliations:

• Vice Chairman for Outpatient Medicine
  Ohio State Univeristy Department of Internal Medicine, 2005 - present
• Professor of Clinical Medicine, Division of Pulmonary and Critical Care Medicine
  2003 - present
• Chief of Internal Medicine
  Ohio State University East Hospital, 2003 - present
• Vice Chairman for Clinical Program Development
  Ohio State University Department of Internal Medicine, 2003 - 2005
• Editor and Moderator
  Ohio State University MedNet, 2002 - present
• Co-Director
  Medical Intensive Care Unit, Ohio State University Hospitals, 2001-2004
• Treasurer
  Department of Medicine Foundation of Ohio, 2001 - present
• Editor and Moderator
  Ohio Medical Education Network (OMEN-TV), 1998 - 2002
• Associate Professor of Medicine
  Division of Pulmonary and Critical Care Medicine, The Ohio State University, 1997 - 2003
• Medical Director
  Medical Intensive Care Unit, Ohio State University Hospitals, 1997 - 2001
• Associate Clinical Director
  Division of Pulmonary and Critical Care Medicine, 1996 - 2002
• Associate Medical Director
  Select Specialty Hospital of Columbus, 1996 - present
• Medical Director
  Pulmonary Diagnostics Laboratory, Ohio State University Hospitals, 1995 - present
• Assistant Professor of Medicine
  Division of Pulmonary and Critical Care Medicine, The Ohio State University, 1991 - 1997

Partial List of Publications:

• Drug induced eosinophilic lung disease
  Allen JN. Clinics In Chest Medicine. 2004; 25:77-88.
• Airway Stents; Self-expandable Metallic
  Allen JN. In: Interventional Bronchoscopy (editors: John F. Beamis, M.D., Praveen Mathur, M.B.B.S., and Athul Mehta, M.D.), 2004.
• The role of microvascular injury in the evolution of idiopathic pulmonary fibrosis
  Magro CM, Allen J, Pope-Harman A, Waldman WJ, Moh P, Rothrauff S, Ross P. Am J Clin Pathol 2003; 119: 556-67.
• Eosinophilic Pulmonary Syndromes
  Allen JN. In: Textbook of Pulmonary Diseases, Seventh Edition. (editors: Crapo jD, Glassroth J, Karlinsky J, and King TE. 2003. 521-38.
• The Eosinophilic Pneumonias
  Allen JN, Magro CM, King MA. Seminars in Respiratory and Critical Care Medicine. 2002; 2:127-134.
• Bedside tracheostomy in the intensive care unit: a prospective randomized trial comparing open surgical tracheostomy with endoscopically guided percutaneous dilational tracheotomy
  Massick DD, Yao S, Powell DM, Griesen D, Hobgood T, Allen JN, Schuller DE. Laryngoscope. 2001; 111:494-500.
• Transfusion-associated graft-versus host disease: A fatal case caused by blood from an unrelated HLA homozygous donor
  Gorman TE, Julius CJ, Barth R, Ng A, Kennedy MS, Prior TW, Allen J, Lasky L. American Journal of Clinical Pathology. 2000; 113:732-7.
• Phase II Trial: Induction paclitaxel in previously untreated, resectable, advanced squamous cell carcinoma of head and neck
  Grecula JC, Smith RE, Rhoades CA, Sharma P, Agrawal A, Zhang H, Allen J, Goldman FP, Young D, Schuller D. Cancer. 2000;89:2587-96.
• Measurement of outcomes in adult patients receiving pharmaceutical care in a comprehensive asthma clinic
  Knoell DL, Pierson JF, Marsh CB, Allen JN, Pathak DS.Pharmacotherapy. 1998; 18:1365-74.
• The use of expandable metal stents to facilitate extubation in patients with large airway obstruction
  Shaffer JP, Allen JN. Chest. 1998; 114:1378-82.
• Churg-Strauss syndrome associated with zafirlukast
  Knoell DL, Allen JN. Chest. 1998; 114:332-3.
• Changes in mononuclear phagocyte microtubules after endotoxin stimulation: I. Changes in microtubule stability
  Allen JN, Moore SA, Liao Z, Wewers MD. American Journal of Respiratory Cell and Molecular Biology. 1997, 16:119-26.
• Changes in mononuclear phagocyte microtubules after endotoxin stimulation: II. Changes in microtubule composition
  Allen JN, Liao Z, Moore SA, Wewers MD. American Journal of Respiratory Cell and Molecular Biology. 1997, 16:127-32.
• Acute eosinophilic pneumonia: A summary of fifteen cases and review of the literature
  Pope-Harman AL, Davis WB, Christoforidis AJ, Allen ED, Allen JN. Medicine 1996; 75:334-332.
• Acute eosinophilic pneumonia: Radiologic and clinical features
  King MA, Pope-Harman AL, Allen JN, Christoforidis GA, Christoforidis AJ. Radiology. 1997; 203:715-9.
• Detection of interleukin-5 and interleukin-1 receptor antagonist in bronchoalveolar lavage in acute eosinophilic pneumonia
  Allen JN, Liao Z, Wewers MD, Altenberger EA, Moore SA, Allen ED. Journal of Allergy and Clinical Immunology. 1996, 97:1366-1374.
• Eosinophils and the lung
  Allen JN, Davis WB. In: The Lung: Scientific Foundations, edited by Crystal RG, West J, Weibel E, and Barnes PL. New York: Raven Press, Ltd., 1996.
• Immunosuppressive properties of surfactant an plasma on alveolar macrophages
  Allen JN, Moore SA, Pope-Harman AL, Marsh CB, Wewers MD. Journal of Laboratory and Clinical Medicine. 1995; 125:356-69.
• A Phase II Trial Of Taxol In Squamous Cell Carcinoma Of The Head And Neck With Correlative Laboratory Studies
  Smith RE, Thornton DE, Allen, JN. Seminars in Oncology. 1995; 22S:41-46.
• Taxol and colchicine increase proIL-1 beta production without affecting processing and release of mature IL-1 beta
  O'Brien JM, Moore SA, Wewers MD, Allen JN. Journal of Immunology. 1995; 154:4113-4122.

Research:

• "Initial safety and pharmacokinetics trial of immune globulin Staphylococcus aureus capsule polysaccharide (Altastaph) in subjects with S. aureus bacteremia and persistent fever"
  Nabi Pharmaceuticals: 2004-2005. Principal Investigator.
• "LIPOS-Lipid Infusion and Patient Outcomes in Sepsis"
  GlaxoSmithKline: 2004-2006. Principal Investigator.
• "A randomized, double-blind, placebo-controlled, phase 3 study of the safety and efficacy of interferon gamma-1b in patients with idiopathic pulmonary fibrosis (INSPIRE Trial)"
  Intermune Pharmaceuticals: 2004-2008. Principal Investigator.
• "E5564 -A001-201 A Double Blind, Placebo-Controlled, Study of E5564, in a Lipid A Antagaonist, Administered by Twice Daily Intravenous Infusions in Patients with Severe Sepsis"
  Eisai Medical Research, Inc: 2003-2004. $67,055. Principal Investigator.
• "Symbicort in asthma"
  Astra-Zenica: 2003-2004. Principal Investigator.
• "A Comprehensive Program for the Prevention, Detection, and Treatment of Lung Cancer"
  Ohio BRTT: 2003. $8,000,000. Co-Investigator.
• "Venticute (rSP-C Surfactant) in Patients with Pneumonia or Aspiration of Gastric Contents Leading to Intubation, Mechanical Ventilation, and Severe Oxygenation Impairment"
  Altana: 2003-2005. Principal Investigator.
• "Study of the tolerablility of 100% ethanol of 20% PEG300/80% ethanol vehicle administrated to subjects with known asthma using a new inhalation device (CDD-2)"
  BattellePharma, Inc.: $145,225. 2002-2003. Principal Investigator.
• "Linezolid versus vancomycin or oxacillin/dicloxacillin in the Treatment of Catheter-related Gram-Positive Bloodstream Infections"
  Pharmacia, Inc.: $45,000. 2002-2004. Principal Investigator.
• "A phase II multicenter randomized double blind placebo controlled parallel group dose ranging evaluation of the safety and efficacy of a-hANP infusion (Carperitide for injection; SUN4936)"
  Suntory Pharmaceuticals: $50,000 estimated.2001-2002 Principal Investigator for the Ohio State University site.
• "Phase III study to demonstrate the safety and efficacy of recombinant platelet activating factor acetylhydrolase (is rPAF-AH, PAFHFE for reducing 28 day all cause mortality in patients with severe sepsis)"
  ICOS Pharmaceuticals: $50,000 estimated. 2001-2002 Principal Investigator for the Ohio State University site.
• "The Anemia of Critical Illness and Transfusion in the Critically Ill Patient"
  Ortho Biotech: $26,000; 2000-2001: Principle Investigator.
• Effects of a corticosteroid-sparing dose of salmeterol/fluticasone propionate combination product
  Glaxo Wellcome, Inc.: 2000-2001 $20,185 Principle Investigator for the Ohio State University site.
• "Phase I and clinical pharmacologic study of inhaled doxyrubicin in adults with advanced stage solid tumors affecting the lung" $
  BattelleParma, Inc.: 20,260. 2000-2003. Co-Investigator.
• "Venticute (rSP-C Surfactant) for the Treatment of Acute Respiratory Distress Syndrome (ARDS): A randomized, multinational, multicenter, parallel group, double blind controlled study"
  Altana/Byk-Gulden Corp.: $36,480; 1999-2000: Principle Investigator for Ohio State University site.

Partial List of Presentations:

• "The Eosinophilic Lung Diseases"
  American Academy of Allergy, Asthma, and Immunology Annula Meeting 2005
• "Pre-operative Pulmonary Evaluation"
  OSU Department of Surgery Grand Rounds 2005
• "Pulmonary Embolism"
  Columbus Children's Hospital, 2005
• "Eosinophilic Lung diseases"
  Lakewood Hospital, Cleveland, Ohio, 2005
• "Pulmonary Fibrosis"
  Blanchard Valley Hospital, Findlay, Ohio, 2005
• "Moderate and Deep Sedation"
  University Hosptials Consortium webcast 2004
• "Pulmonary Function Testing"
  OSU Department of Anesthesiology Grand Rounds 2004
• "Interventional Bronchoscopy"
  11th Annual Pulmonary Update 2004
• "Interventional Bronchoscopy"
  OSU Department of Internal Medicine Grand Rounds 2004
• "Idiopathic Pulmonary Fibrosis"
  Ohio Thoracic Society Annual Meeting 2003
• "Pro-Con: Early Idiopathic Pulmonary Fibrosis Should Be Treated"
  American College of Chest Physicians, Orlando, Florida, 2003
• "Pro-Con: Controversies in Pulmonary Embolism"
  OSU Department of Internal Medicine Grand Rounds 2003
• "Interstitial Lung Disease"
  10th Annual Pulmonary Update 2003
• "Pulmonary Embolism"
  OSU East Hospital Grand Rounds 2003
• "Pulmonary Embolism"
  Ohio University: Columbus, Ohio, 2003
• "The Eosinophilic Lung Diseases"
  Medical University of South Carolina Department of Internal Medicine Grand Rounds 2002
• "Mechanical Ventilation"
  9th Annual Pulmonary Update 2002
• "Breathing New Life Into Old Diseases - Update On Mechanical Ventilation"
  23rd Annual Critical Care Course Medical College of Georgia; Sea Island, Georgia 2001
• "Plumbing Repair In The ICU - Approach To Large Airway Obstruction"
  23rd Annual Critical Care Course Medical College of Georgia; Sea Island, Georgia 2001
• "Pulmonary Embolus"
  8th Annual Pulmonary Update 2001
• "Idiopathic Pulmonary Fibrosis"
  8th Annual Pulmonary Update 2001
• "CPC: Scleroderma Lung Disease"
  OSU Department of Internal Medicine Grand Rounds 2001
• "ARDS: Improved Mortality For The Wrong Reasons"
  OSU Department of Internal Medicine Grand Rounds 2001
• "Pulmonary Embolism"
  Chillicothe VA Hospital: Chillicothe, Ohio, 2001
• "ARDS Update"
  Camden Clark Hospital, Parkersburg, WV 2001
• "ARDS Update"
  Chillicothe VA Hospital: Chillicothe, Ohio, 2001
• "Lung Cancer treatment"
  7th Annual Pulmonary Update 2000
• "Pulmonary Fibrosis"
  OSU Department of Internal Medicine Grand Rounds 2000
• "Hypercoaguable States"
  OSU Department of Internal Medicine Grand Rounds 2000
• "Pulmonary Fibrosis"
  Chillicothe VA Hospital: Chillicothe, Ohio, 2000
• "Pulmonary Embolism"
  Springfield Mercy Medical Center, Springfield, OH, 2000
• "Pulmonary Thromboembolism"
  6th Annual Pulmonary Symposium 1999
• "Lung Cancer"
  6th Annual Pulmonary Symposium 1999
• "Pulmonary Embolism"
  OSU Department of Internal Medicine Grand Rounds 1999
• "Pulmonary Embolism"
  OSU Departement of Physical Medicine Grand Rounds 1999
• "Pulmonary Embolism"
  Columbus Children's Hospital Department of Pediatrics Grand Rounds 1999
• "Lung Cancer Update"
  OSU Department of Internal Medicine Grand Rounds 1999
• "Eosinophilic Lung Disease"
  American Thoracic Society; Chicago, Illinois 1998
• "Pulmonary Quiz"
  Ohio Medical Education Network (OMEN) 1998
• "Tracheobronchial Stents"
  5th Annual Pulmonary Symposium 1998
• "Tracheobronchial Stents"
  OSU Respiratory Therapy Update Symposium 1998
• "Is There A Best Way To Wean?"
  OSU Respiratory Therapy Update Symposium 1998
• "The Pulmonary Patient In Long Term Acute Care Hospitals"
  OSU Case Managers Symposium 1998
• "Interventional Bronchoscopy"
  Charleston Pulmonary Symposium; Charleston, South Carolina 1997
• "Eosinophilic Lung Disease"
  American College of Chest Physicians New Orleans, Lousianna 1997
• "Update in Mechanical Ventilation"
  Ohio Medical Education Network (OMEN) 1997
• "Approach To Large Airway Obstruction"
  OSU Department of Internal Medicine Grand Rounds 1997
• "Pulmonary Thromboembolism"
  OSU Department of Obstetrics and Gynecology Grand Rounds 1997
• "Acute Eosinophilic Pneumonia"
  American Thoracic Socity; New Orleans, Lousianna 1996
• "The Eosinophilic Lung Diseases"
  OSU Department of Internal Medicine Grand Rounds 1996
• "Non-Invasive Ventilation in COPD"
  4th Annual Pulmonary Symposium 1996
• Ohio Medical Education Network (OMEN) 1996 "Update on COPD"
• "Asthma Update"
  OSU Department of Internal Medicine Grand Rounds 1996
• "The Eosinophilic Lung Diseases"
  Charleston Pulmonary Symposium; Charleston, South Carolina 1995
• "When The Cause Of Respiratory Failure Is Non-Infectious"
  3rd Annual Pulmonary Symposium, 1995
• "Tuberculosis Update"
  Ohio Medical Education Network (OMEN) 1995
• "Acute Ventilator Therapy"
  8th Annual Cardiology Symposium 1995
• "Update on the Treatment of COPD"
  OSU Department of Internal Medicine Grand Rounds 1995

Awards:

• 2007 Best Doctors in America®
• Ohio State University Department of Internal Medicine Critical Care Teaching Award, 2005
• Named among "The Best Doctors in America", 2005
• Named among "The Best Doctors in Columbus", Columbus Monthly Magazine, 2005
• Named among "The Top Pulmonologists in Columbus", Columbus Dispatch Newspaper, 2004
• Ohio State University Department of Internal Medicine Teacher Of The Year Award, 2004
• Ohio State University Department of Internal Medicine Teacher Of The Year Award, 2003
• Named among "The Best Doctors in America", 2003
• Ohio State University Department of Internal Medicine Teacher Of The Year Award, 2001
• Ohio State University College of Medicine Teaching Award, 2000
• Battelle Professor of Inhalational Therapeutics, 2000
• Named among "The Best Doctors in America", Woodward/White, Inc., 1998
• Named among "The Top Doctors in Columbus", Columbus Monthly Magazine, 1998
• Crystal Cross Award, American Lung Association of Ohio, 1997
• Professor of the Year, Ohio State University College of Medicine, 1996.
• OMEN TV Best Clinical Presentation of 1995-96.
• Ohio State University Department of Internal Medicine Teacher Of The Year Award, 1994.
• OMEN TV Best Team Clinical/Surgical Presentation of 1994-95.
• Ohio State University CME Award of Excellence, 1994-95.
• James V. Waren Award for Fellowship Research, Ohio State University, 1991.

Web Links:

• Coalition for Pulmonary Fibrosis: Directory
• Idiopathic Pulmonary Fibrosis
• Pulmonary Fibrosis (Patient Education Materials)

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