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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Sunday, September 7, 2008
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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Sunday, September 7, 2008
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The University of Cincinnati's Division of Transplantation is one of the oldest academic transplant divisions in the United States, having performed its first transplant over 40 years ago. The division staff's internationally renowned care programs are in kidney, pancreas and liver transplantation and research.
It is a leader in innovative approaches including laparoscopic nephrectomy, immunosuppressive drug development, cancer and transplantation, corticosteroid elimination, laparoscopic liver surgery, dialysis access research and the development of paired donation programs.
The division has developed a world-class immunosuppressive drug development program. This has been accomplished as a team effort between the division and the section of transplant nephrology. Funded studies include two large, multi-center trials, one being a large, NIH-sponsored randomized clinical trial of therapy for post-transplant lymphoproliferative disorder in renal transplant recipients.
The division of transplantation has also collaborated with the University of Louisville on a recent study published in the September edition of the journal Plastic and Reconstructive Surgery showing that immunosuppressive risks associated with facial transplantation may be lower than thought.
In the study, Cincinnati and Louisville researchers compared older, more controversial predictions with actual data taken from clinical studies describing kidney and hand transplants using the latest immunosuppression techniques.
Based on kidney and hand transplantation cases, in which the same drug regimen was used, researchers found that acute, or immediate, rejection may occur in 10 to 70 percent of patients. In of all these cases, however, rejection was reversible by adjusting the immunosuppression medications.
They also found that fewer than 10 percent of patients would experience chronic rejection over five years.
The division also continues to fill its American Society of Transplant Surgeons (ASTS) certified transplant fellowship training program with fellows of the highest quality. Great emphasis is placed on inviting speakers of national and international stature to present at Transplant Grand Rounds.
Our NetWellness expert from the Division of Transplantation is Dr. Steve Rudich, who answers questions for the Digestive Disorders health topic.
This article is a NetWellness exclusive. 
Last Reviewed: Sep 25, 2007
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