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Lung Cancer

Stage 3 Non-Small Cell Lung Cancer

Stage IIIA

Stage IIIA is divided into three sections depending on the size of the tumor, where the tumor is found, and which lymph nodes have cancer (if any).

Stage IIIA non-small cell lung cancer (1). Drawing shows cancer in lymph nodes, left main bronchus, and diaphragm; there may be separate tumors in the same lung; the trachea is also shown. Top inset shows cancer that has spread from the lung through the lung lining and chest wall lining into the chest wall; a rib is also shown. Bottom inset shows the heart and cancer that has spread from the lung into the membrane around the heart.

(1) Cancer has spread to lymph nodes on the same side of the chest as the tumor. The lymph nodes with cancer are near the sternum (chest bone) or where the bronchus enters the lung. Also:

  • The tumor may be any size.
  • Part of the lung (where the trachea joins the bronchus) or the whole lung may have collapsed or developed pneumonitis (inflammation of the lung).
  • There may be one or more separate tumors in the same lobe of the lung.
  • Cancer may have spread to any of the following:
    • Main bronchus, but not the area where the trachea joins the bronchus.
    • Chest wall.
    • Diaphragm and the nerve that controls it.
    • Membrane around the lung or lining the chest wall.
    • Membrane around the heart.

or

 

Stage IIIA lung cancer  (2). Drawing shows cancer in the lymph nodes, trachea, carina, left main bronchus, esophagus, sternum, diaphragm, and major blood vessels that lead to or from the heart; there may be separate tumors in the same lung. Top inset shows cancer that has spread from the lung through the lung lining and chest wall lining into the chest wall; a rib is also shown. Bottom inset shows cancer that has spread from the lung, through the membrane around the heart, into the heart.

(2) Cancer has spread to lymph nodes on the same side of the chest as the tumor. The lymph nodes with cancer are within the lung or near the bronchus. Also:

  • The tumor may be any size.
  • The whole lung may have collapsed or developed pneumonitis (inflammation of the lung).
  • There may be one or more separate tumors in any of the lobes of the lung with cancer.
  • Cancer may have spread to any of the following:
    • Main bronchus, but not the area where the trachea joins the bronchus.
    • Chest wall.
    • Diaphragm and the nerve that controls it.
    • Membrane around the lung or lining the chest wall.
    • Heart or the membrane around it.
    • Major blood vessels that lead to or from the heart.
    • Trachea.
    • Esophagus.
    • Nerve that controls the larynx (voice box).
    • Sternum (chest bone) or backbone.
    • Carina (where the trachea joins the bronchi).

or

Stage IIIA non-small cell lung cancer (3). Drawing shows cancer in the heart, major blood vessels that lead to or from the heart, the trachea, esophagus, sternum, and carina; the diaphragm is also shown. Inset shows cancer that has spread from the lung, through the membrane around the heart, into the heart.

(3) Cancer has not spread to the lymph nodes and the tumor may be any size. Cancer has spread to any of the following:

  • Heart.
  • Major blood vessels that lead to or from the heart.
  • Trachea.
  • Esophagus.
  • Nerve that controls the larynx (voice box).
  • Sternum (chest bone) or backbone.
  • Carina (where the trachea joins the bronchi).

Stage IIIB

Stage IIIB is divided into two sections depending on the size of the tumor, where the tumor is found, and which lymph nodes have cancer.

Stage IIIB non-small cell lung cancer (1). Drawing shows cancer in lymph nodes above the collarbone on the opposite side of the chest as the primary tumor, and in the trachea, carina, left main bronchus, esophagus, sternum, diaphragm, and major blood vessels that lead to or from the heart; there may be separate tumors in the same lung. Top inset shows cancer that has spread from the lung, through the lung lining and chest wall lining, into the chest wall; a rib is also shown. Bottom inset shows cancer that has spread from the lung, through the membrane around the heart, into the heart.

(1) Cancer has spread to lymph nodes above the collarbone or to lymph nodes on the opposite side of the chest as the tumor. Also:

  • The tumor may be any size.
  • Part of the lung (where the trachea joins the bronchus) or the whole lung may have collapsed or developed pneumonitis (inflammation of the lung).
  • There may be one or more separate tumors in any of the lobes of the lung with cancer.
  • Cancer may have spread to any of the following:

or

Stage IIIB non-small cell lung cancer (2). Drawing shows cancer in lymph nodes on the same side of the chest as the primary tumor, in the heart, major blood vessels that lead to or from the heart, the trachea, esophagus, sternum, carina, and in separate tumors in different lobes of the same lung; the diaphragm is also shown. Inset shows cancer that has spread from the lung, through the membrane around the heart, into the heart.

(2) Cancer has spread to lymph nodes on the same side of the chest as the tumor. The lymph nodes with cancer are near the sternum (chest bone) or where the bronchus enters the lung. Also:

  • The tumor may be any size.
  • There may be separate tumors in different lobes of the same lung.
  • Cancer has spread to any of the following:
    • Heart.
    • Major blood vessels that lead to or from the heart.
    • Trachea.
    • Esophagus.
    • Nerve that controls the larynx (voice box).
    • Sternum (chest bone) or backbone.
    • Carina (where the trachea joins the bronchi).

Adapted from the National Cancer Institute's Physician Data Query (PDQ(r)) Cancer Information Summaries (http://www.cancer.gov/cancertopics/pdq). Date Last Modified: April 2, 2015

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Last Reviewed: Apr 07, 2015