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Pharmacy and Medications

Difference Between Shelf Life and Expiration Date of a Medication

The term "shelf life" of a drug slightly differs from a drug's "expiration date". The shelf life generally relates to a drug's quality, whereas the expiration date relates to its safety.

Shelf Life - A drug that has passed its shelf life might still be safe for consumption, but its quality is no longer guaranteed. Shelf life is variably influenced by storage conditions, such as exposure to heat, light and moisture.

Expiration Date and Safety - The expiration date of a medication indicates the date the manufacturer or pharmacist guarantees the full potency and safety of a drug. Some, but not all medications retain potency and are usually safe briefly following the expiration date, but you must check with a pharmacist about specific medications. Some drugs, such as tetracycline antibiotics, can be dangerous if used after their expiration date.

Which Date To Follow

If a bottle has both the shelf life & expiration date listed, then it is advisable to use the earlier date as the time to avoid consumption. However, better still would be handing the dosage unit to your pharmacists so he or she can give you specific advice.

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Last Reviewed: Aug 26, 2009

Case Western Reserve University Darrell Hulisz, RPh, PharmD
Associate Professor
Department of Family Medicine
University Hospitals
School of Medicine
Case Western Reserve University
Darrell   Hulisz, RPh, PharmD