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Thursday, January 29, 2015
ASBESTOSIS VS. IPF
what is the best way to differentiate between IPF and Asbestos related lung diseases?
This is a difficult question. The two diseases are indistinguishable on biopsy specimens. Even demonstrating the presence of `asbestos bodies` on the lung biopsy does not prove that the disease is due to asbestos, since these can also been seen in IPF. The best indicators of asbestosis are: 1) a compatible exposure history, 2) pleural thickening on chest xray or high resolution CT, 3) pleural calcification on chest xray or chest CT. The latter is the most specific.
Francis X McCormack, MD
Professor of Medicine
College of Medicine
University of Cincinnati