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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Thursday, March 11, 2010
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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Thursday, March 11, 2010
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Digestive Disorders |
Sinequan`s effects on Allergies and IBS01/31/2001 |
My wife began taking Sinequan in 1979 following childbirth and a severe case of post partum depression. After one year, she had reduced the daily dosage to 25mg, but finally quit.She had a series of intestinal problems akin to Irritable Bowel Syndrome, and after a series of other events, began to take Sinequan again, and did so for nearly 16 years.
She has been off Sinequan now for 8 months but there IBS symptoms have returned and she suffers other symptoms that appear to be allergies to environment and foods.
Our GP is a competent doctor, but not familiar with allergies, and hestitant to prescribe a maintenance dose of Sinequan (i.e 10 mg) for relief of the IBS and allergy symptoms.
Are there other medications that would have the same effects? Is there any clinic study or research that recommends the use of Sinequan to treat IBS or Allergies to you could recommend for me to read, or share with my GP?
Thanks
Irritable bowel syndrome can be treated with some success by tricyclic antidepressants such as Sinequan (doxepin). I am not aware of any formal studies that specifically used doxepin but there are studies that used some of the other tricyclics (such as amitriptyline, nortriptyline, etc.). It sounds like your wife has less IBS symptoms when she is on the doxepin and there is no reason for her not to take it if it helps. A recent article in the July 18 issue of the Annals of Internal Medicine reviews some of the above studies.
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John D. Long, MD Assistant Professor of Clinical Medicine Division of Digestive Diseases Department of Internal Medicine College of Medicine University of Cincinnati |
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