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ANA and Cloroquine



Can chloroquine cause a false positive ANA test?


Cloroquine is an antimalarial drug which was also used to treat Lupus. More recently Plaquenil (Hydroxychloroquine) is used for certain cases of lupus. None of them is among the medications - even in the most extended list that I have seen - who induce positive ANA or drug-lupus. I never saw in the literature any case reports of cloroquine inducing ANA or lupus. If the cloroquine was given to a patient for lupus that would explain the positive ANA.

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Response by:

Yolanda   Farhey, MD Yolanda Farhey, MD
Associate Professor
College of Medicine
University of Cincinnati