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Monday, May 1, 2017
How bad is the effect of giving Benadryl to a Myasthenia Gravis patient?
I prefer not to use anticholinergics more because of sedating and suppression of cough actions. The medicines have other disturbing side effects. I recommend using the selective antihistaminic medicines (Zyrtec, Allegra, etc.).
If a patient`s MG is completely controlled and the other side-effects of anticholinergic medicines are not an issue, Benadryl could be used just because of cost concerns (the other medicines are very expensive).
Thanks for your question.
John G Quinlan, MD
Professor of Neurology
College of Medicine
University of Cincinnati