Senior Health |
Neuropathy and Zoloft03/06/2001 |
I have neuropathy in my foot. Along with neurontin my doctor has recommended taking zoloft for the beneficial side effects of the drug. How does this work to reduce the pain?
Zoloft (sertraline), a SSRI antidepressant, is an adjuvant in chronic pain relief of neuropathic origin by altering the neurotransmitters in the brain and also helping depression/anxiety associated with chronic pain, sort of breaks the cycle of pain-depression-heightened pain awareness. SSRI are safer agents compared to the tri-cyclic agents (Amitriptyline) used as adjuncts in pain management in the past and now being frequently used.
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Elizabeth Joyner Gothelf, BSN, MAG Assistant Director College of Medicine University of Cincinnati |
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Arvind Modawal, MD, MPH, MRCGP Professor of Family & Community Medicine, Geriatrics and Palliative Care College of Medicine University of Cincinnati |