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Mesial temporal sclerosis



I am not even sure this is related to epilepsy. What is mesial temporal sclerosis, what are the symptoms, treatment, and prognosis? Thanks for your assistance.


Mesial temporal sclerosis describes the pathology in many patients with temporal lobe epilepsy. It is scar tissue in the deeper structures of the temporal lobe. This can often be identified on MRI scans and usually is where the seizure starts. It may be caused by some early neurologic injury, although in many patients, the cause cannot be identified. The presence of mesial temporal sclerosis usually indicates poorly controlled seizures.

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Response by:

David M Ficker, MD David M Ficker, MD
Associate Professor
College of Medicine
University of Cincinnati