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Friday, March 7, 2014
Immuran vs Cyclosporine
I have been on Prednisone for over 10 months and my Dr. is going to take me off the drug and give me either Immuran or Cyclosporine. If there is a choice which one would be better?
The choice between Imuran (azathioprine) and cyclosporine (Neoral, Sandimmune)is dependent on your particular condition and other medical problems. Imuran is not effective for 6 to 9 months. Ten percent of patients treated Imuran develop of flu-like reaction to the drug and it needs to be discontinued in the first months of treatment. Imuran may effect liver function and this requires monitoring. Cyclosporine requires 3-6 months to begin to take effect, but may produce high blood pressure and affect kidney function (this also requires monitoring). Patients of mine have improved with either of these medications.
Henry J Kaminski, MD
Formerly, Professor of Neurology
School of Medicine
Case Western Reserve University