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Inherited Disorders and Birth Defects

Biology project

04/09/2002

Question:

i am doing a biology project on cleft palate and is there any info u can give me on it thank you sara

Answer:

Cleft lip with or without cleft palate is a very common birth defect. About 1 out of 700 to 1000 newborns are born with a cleft lip and/or cleft palate.

Failure of the lip and/or palate (roof of the mouth) to close happens early in gestation - about 6-8 weeks of pregnancy. Surgery following birth usually has excellent results.

Usually, isolated (no other birth defects present) cleft lip and/or cleft palate is due to a combination of genetics and environmental factors. The chance it could happen again is based on many factors including the number of affected persons in a family, the closeness (blood relation) of affected relatives, race, sex and the severity of the clefts.

There is excellent information available regarding cleft lip and/or cleft palate at the following websites: Cleft Palate Foundation, the March of Dimes, and a number of sites listed through the University of Kansas Medical Center Genetics Education site.

Good luck with the project.

Related Resources:

Cleft Palate Foundation
March of Dimes Fact Sheets
University of Kansas Medical Center Genetics Education

For more information:

Go to the Inherited Disorders and Birth Defects health topic, where you can:

Response by:

Case Western Reserve University Anne Matthews, RN, PhD
Director, Genetic Counseling and Family Studies
Associate Professor
Department of Genetics
School of Medicine
Case Western Reserve University
Anne   Matthews, RN, PhD