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Kidney Diseases

Kidney stones and infection

02/02/2004

Question:

My mother has been in and out of the hospital since October 2003. She has only one kidney. When her problems started in October she had kidney stones. When her doctor went in to remove them he found a lot of infection along with a substance they have referred to as "Matrix." She has had at least one surgery a month since October. She is now back in the hospital with kidney stones which they have removed, but the infection is still really bad and is now in her blood stream. The next procedure she has been told they need to do is put a drain in her side to suck all the infection out. Can you please give me any advise on her condition. As I said she only has one kidney.

Thank You.

Answer:

Usually infections are treated with some form of antibiotic drug, depending on what the infectious agent (bug) is susceptible to. If the organ involved has had its blood supply reduced, for any reason, the drug used, which gets there from the blood, may not reach the infectious agent in high enough concentration to kill the ‘bug’. So the damage continues to occur to the organ and the ‘bug’ continues to damage the organ infected. Then the bug will get into the blood supply and look for other places to find what it needs.

The term matrix refers to the material that holds the organ together. It exists in the kidney around the individual functioning units of the kidney (nephrons). Infections in the matrix are more difficult to treat than those in the nephron itself.

This is a complicated answer to your question. This is apparently the condition that your mother is in now. I hope it helps. I would urge your mother to follow through quickly with the procedures her physicians want to do.

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Response by:

Case Western Reserve University Philip W Hall, 3rd, MD
Formerly, Professor Emeritus of Medicine
Office of Medical Education
School of Medicine
Case Western Reserve University
Philip W Hall, 3rd, MD