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Wednesday, February 8, 2012
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Lung Center |
Tracheoesophageal fistula05/26/2004 |
what is the history of this disorder/ where did it come from? genes...?
Tracheoesophageal fistula (TEF) may be congenital or acquired. The congenital form is diagnosed in neonates (infants) and is typically associated with esophageal atresia. It is managed surgically, usually by pediatric surgeons in a children`s hospital experienced in managing this complex disorder. See: Manning PB, et al. Ann Surg 1986;204:446-53. Acquired TEF may be malignant or benign. In the malignant form the primary tumor is usually of esophageal origin, but may also be from the lung, trachea, larynx, thyroid, or lymph nodes. Malignant TEF should usually be managed by palliation, often with stenting. Acquired nonmalignant TEF can occur from a variety of causes, including trauma, infection, surgery, and AIDS; but the most common cause is mechanical ventilation. Treatment is with surgery, ideally by a thoracic surgeon experienced in complicated airway and esophageal cases. See: Reed MF and Mathisen DJ. Chest Surg Clin N Am 2003;13:271-289. I am not aware of any specific genetic abnormalities predisposing to TEF.
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Michael F Reed, MD Assistant Professor of Surgery Division of Thoracic Surgery Department of Surgery College of Medicine University of Cincinnati |
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