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Wednesday, April 16, 2014
HIV and AIDS
What Are The Details Of The HIV-PCR Test?
Please explain HIV-PCR test. How reliable is it when done in conjunction with a standard test, (log? or elisa?), one year after probable exposure?
The standard serologic test consists of a screening ELIZA followed by a confirmatory WB. This test shows sensitivity and specificity rates of >98%.
There are several commercially available assays that reliably quantitate HIV RNA in plasma. HIV RNA PCR has a sensitivity of 95-98% .
These tests if negative at 1 year after exposure can effectively rule out HIV infection.
Pamposh Kaul, MD
College of Medicine
University of Cincinnati