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Infectious Diseases

Nitrofurantoin and birth control pills

12/22/1998

Question:

Does macrobid reduce the effectiveness of birth control pill like some antibiotics do?

Answer:

Macrobid is Proctor and Gamble's trade name version of the antibioitic nitrofurantoin. This antibiotic does not decrease the effectiveness of oral or injectable hormonal birth control. Medications that do this are usually inducers of liver metabolism. An example of such a drug is rifampin, which is used to treat tuberculosis and other mycobacterial infections.

Nitrofurantoin is indicated only for the treatment of uncomplicated urinary tract infections caused by susceptible strains of E. coli or Staph. saprophyticus.

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Response by:

Kenneth   Skahan, MD Kenneth Skahan, MD
Assistant Professor in Infectious Diseases
College of Medicine
University of Cincinnati