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Anesthesia

Anesthetic drugs

10/10/2005

Question:

Hi can you tell me if this is normal in an operation for a gallbladder removal, that these drugs are used brietal, scoline, pavulon, atropine, neostigmine if at the time no known muscle weakness , would be grateful for any information.

Answer:

An operation for gall bladder removal usually requires a general anesthetic.  During a normal general anesthetic, a variety of different anesthetic drugs are used.  There are drugs given into a vein (intravenous) that send you into an unconscious state or keep you in that state, inhaled anesthetic agents (gases) that also maintain unconsciousness, drugs used to relax (paralyzes) your muscles, drugs used to treat pain, drugs used to reverse the effects of the muscle relaxants, and drugs used to support your heart or blood pressure.

The drugs you mention are all medicines used in general anesthesia.  Brietal is also known as methohexital and is an intravenous anesthetic agent.  Scoline (siccinylcholine) and Pavulon (pancuronium) are both muscle relaxants.  Atropine and neostigmine are two drugs used together to reverse the effects of muscles relaxants at the end of surgery.  I am not sure what your concern is about muscle weakness.   As noted, two of the drugs you mention are muscle relaxant, or paralyzing, drugs.  Some of the effects of these drugs can occasionally extend into the recovery period when patients are now awake, causing usually mild, but sometimes distressing muscle weakness.

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Response by:

Case Western Reserve University Gareth S Kantor, MD
Assistant Professor
Department of Anesthesiology
University Hospitals
School of Medicine
Case Western Reserve University
Gareth S Kantor, MD