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Osteoporosis

ONJ and Zometa

10/26/2006

Question:

I have taken one intravenous dose of Zometa and am due for the second. Is Zometa associated with bone death?

Answer:

High doses of intravenous bisphosphonates have been associated with poor healing in the jaw bone after dental procedures primarily in patients with cancer.  It is a rare event, but to be cautious you can discontinue the medication if you need to have a dental procedure that involves the bone.  You can restart the medication once you have completely healed from the procedure.

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Response by:

Margery   Gass, MD Margery Gass, MD
Formely, Professor, Clinical Obstetrics & Gynecology
College of Medicine
University of Cincinnati