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Thyroid Diseases

Comparing Thyroid Disease and MG

01/31/2007

Question:

What are the symptoms of thyroid diease and how do they compare to MG? I read a post about eye movement and diagnosis of these conditions. How would you be tested for thyroid disease?

Answer:

Myasthenia Gravis is an autoimmune disease characterized by weakness and fatigability of skeletal muscles. Circulatory autoantibodies against neuromuscular junction in this disease have a major role in causing the muscle weakness. Ocular disease, (including muscular weakness) related to Grave's disease, which is also an immune-mediated thyroid disease is associated with higher circulatory autoantibodies against thyroid. Therefore, these diseases can be differentiated based on symptoms and specific circulatory antibodies. Higher thyroid hormone production (hyperthyroidism) can also cause generalized muscle weakness, which is consistent and can be detected by the blood test. 

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Response by:

Marzieh  Salehi, MD Marzieh Salehi, MD
Assistant Professor of Endocrinology
College of Medicine
University of Cincinnati