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Inherited Disorders and Birth Defects

Left umblical artery atresia-teminated baby



Hi, I am 26 yrs old, weight-72 kgs, had pcod problem not conceived for 3 yrs, no contraceptions used. After three yrs with fertyl super conceived. Done scan 4 times scan 1 : 5 wks 6 days found single intrauterine gestation with yolk sak. Scan 2: 7 wks 5 days live intra uterine found Scan 3: 13 wks 5 days-single live intra uterine gestation Scan 4: 22 wks 4 days aged single live festation showing 22 wks 2 days size( 50 th percentile). With left radial and fibular aplasia, left club hand, club foot, left renal aplasia and left umbilical artery artersia. So doctors asked me to terminate. Done by sep-06. They say due to chromosome this has occured. Before pregancy thyroid test has been done-result normal I dont have any problems other than pcod. From my husbands sperm test - its says oligospermia. Parental karyotype done-negative(both) Now I am pregant 6 wks feb-07, my doctor asked me to take folinz and ecosprin(india). Here docors will see me only by 8th week. I am sacred what will happen to this. Can any suggest what are the steps to be done during my pregancy? Is it ok till my doctors see if I take ecosprin and folinz. Please let me know, any suggestions.


I am so sorry for your loss. These are always very difficult decisions.

You need to ask your doctors if they found a specific cause for your first baby’s problems. If they did, then they should be able to tell you what the chance is that this will happen again in another pregnancy. If they were not able to make a diagnosis for your first baby, it is more difficult to say if there is a chance that it will happen again. I assume your doctor will follow your current pregnancy very closely such as with ultrasound.

Ecosprin is a low dose aspirin. It is sometimes given in pregnancy. I do not know what folinz is.

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Response by:

Anne   Matthews, RN, PhD Anne Matthews, RN, PhD
Associate Professor of Genetics
School of Medicine
Case Western Reserve University