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Urinary Disorders

Kidney Damage and Pepto?



Can prolong use of OTC Pepto-Bismol (2 tablespoons twice a day) affect the kidneys, especially if one has a history of marked hydronephrosis and kidney stones?

Thank you.


There is an association between hydronephrosis and kidney stone disease. People with blockage at the junction of the ureter and renal pelvis sometimes developed kidney stone.

There also is an association between ingestion of certain drugs such as TUMS which is loaded with salt and calcium. Pepto-Bismol contains Bismuth, salicylate and Magnesium aluminum silicate but also contains sorbic acid as well. None of which should affect the kidney.

You should increase fluid intake as well as reduce intake of salt, excess calcium and food containing oxalate if you have history of kidney stone disease.

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Response by:

Ahmad  Hamidinia, MD Ahmad Hamidinia, MD
Formerly, Professor of Clinical Surgery
College of Medicine
University of Cincinnati