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Urinary and Genital Disorders (Children)

VUR prophylaxis

11/13/2007

Question:

My 4 yr. old son has been recently diagnosed VUR (right gr.I and left gr. III) in urinary tract. He is on SEPTRAN (Cotrimoxazole ) prophylaxis. One doctor has suggested me 4mg/kg in 2 divided doses of Cotrimoxazole whereas other has given 2 mg/kg at night. What should I do? What precaution should I take so he doesn’t get urine infection again?

Answer:

Generally, 1 - 1 1/2 tsp at bedtime is sufficient. It is important to brush the teeth after giving the medication to prevent dental caries (cavities), because the drug is heavily sweetened.

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Response by:

Jack S Elder, MD, FACS, FAAP Jack S Elder, MD, FACS, FAAP
Clinical Professor of Urology
School of Medicine
Case Western Reserve University