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Androgel, 36 years old, infertility?



My doctor referred me to an endocrinologist who confirmed that I need to be on HRT. My test levels were in the 170`s, LH, FSH, Prolactin, were all ok. So, primary Hypogonadism was the conclusion. They started me on Androgel 2.5. I`ve been on it for about 2 weeks and feel absolutely NO CHANGE. I`m still weak, lethargic, and down in the dumps. Interestingly, libido is not bad and erections are just fine. I was originally questioning the dosage, too low, and I came across a lot of threads disussing how most MD`s don`t really know what they`re doing when it comes to male HRT. They just give you Androgel, don`t consider Clomid, HCG, etc... In addition, there were a lot of posts discussing INFERTILITY!!! I`m 36, divorced cause I wanted kids/she didn`t. So now I`m with someone I`m planning to marry and have children with. I just started Androgel, am I risking becoming STERILE!!?? What should I do?


If you are interested in having children, you should be very careful about taking testosterone therapy or other male hormones as these can significantly decrease sperm counts.  If your testosterone levels are indeed low, HCG or clomiphene citrate (clomid) would be more appropriate if you are trying to conceive.  I would also suggest checking a semen analysis to determine if your testosterone levels are affecting your sperm counts.  I would also suggest repeating your testosterone levels, as well as checking your thyroid function.  Ultimately, you should be evaluated and managed by a urologist who specializes in male factor infertility.

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Response by:

Daniel B Williams, MD Daniel B Williams, MD
College of Medicine
University of Cincinnati