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Anxiety and Stress Disorders

Trazodone Withdrawal



What will happen if you don`t take your Trazadone for a couple of days in a row?


Generally, it takes several days of missing Trazodone for its anti-depressant and chronic pain benefits to start to decrease.  However, when taken to assist with sleep, then missing one dose may make a difference.

While there are some anecdotal reports of withdrawal symptoms like anxiety, jitteriness or uncomfortable feelings, there is no generally recognized withdrawal syndrome. 

Good luck.

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Response by:

Nancy   Elder, MD Nancy Elder, MD
Associate Professor
College of Medicine
University of Cincinnati