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Myasthenia Gravis

Aricept vs Mestinon

01/23/2008

Question:

Since Aricept is a reversible AChE inhibitor is it useful in the treatment of myasthenia gravis. I am on 300mg of Mestinon and 12.5mg of Prednisone daily.

Answer:

Although Aricept is a reversible AChE inhibitor, it works only in the central nervous system. Myasthenia Gravis is a disease of the neuromuscular junction, which is in the peripheral nervous system.

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Response by:

Catherine  Kernich, MSN, RN, CNP Catherine Kernich, MSN, RN, CNP
Formerly
Case Western Reserve University