Home HealthTopics Health Centers Reference Library Research
Join us on Facebook Join us on Facebook Share on Facebook

Sickle Cell Anemia

Sickle Cell Anemia Chromosome Informatiion

01/14/2008

Question:

Which chromosome does the mutation occur upon? Which gene? Where on the chromosome, on both or on one? Thank you

Answer:

The mutation occurs in the 6th codon of the beta globin gene located on chromosome 11. If one gene is affected the individual has sickle trait (carrier) and if both genes are affected the individual has sickle cell disease.

For more information:

Go to the Sickle Cell Anemia health topic, where you can:

Response by:

Anthony D Villella, MD Anthony D Villella, MD
Formerly, Assistant Professor of Pediatrics
School of Medicine
Case Western Reserve University