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Pharmacy and Medications

Is Mefenamic Acid Safe for a Child with Multicystic Dyslastic?

03/27/2008

Question:

One of the kidney of my two years old daughter is Multicystic Dysplastic. She responds very well to the Meftal. But her pediatrician advised not to use Meftal. She has got high fever (respiratory infection) of 104F. We gave her Crocin (paracetamol syrup) and then paracetamol and cetrizine combined syrup, she din’t respond. We gave her only one dose of 2 ml of Meftal-P (Mefenamic acid). Within a short time she responded. We are not at our native place. The place where we are does not have a pediatric neprologist. Kindly advise us whether we can use Meftal for our child or not? If not, then which antipyretic and analgesic will be safe for her at the time of high fever?

Answer:

Mefenamic acid can cause kidney problems and may not be the safest choice for your child. One of your child's doctors who knows her medical conditions well has advised against using Meftal (mefenamic acid). It would seem best not to use mefenamic acid unless her doctors approve. 

Paracetamol or acetaminophen would seem to be appropriate for a fever unless your child's doctor has advised you not to use it. This drug should help with a fever. Was the proper dose given?

Drug doses in a person with decreased kidney function should be carefully prescribed by a doctor. Please discuss your concerns with a physician.

The link below provides additional information on mefenamic acid.

Related Resources:

MedlinePlus

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Response by:

Carmen M Hadley, RPh, CSPI
Former Clinical Instructor
College of Pharmacy
The Ohio State University