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Colorectal Diseases

Granularity of terminal ileum



I am a 37 year old female who recently had a colonoscopy after having a small perforation in her ileum which resolved with antibiotics and rest. The colonoscopy revealed that the colon was normal, but there was some granularity of terminal ileum. What could that possibly mean? Otherwise all else looked normal. I have to wait 2 weeks for results of biopsy.


Full thickness inflammation and perforation of the terminal ileum is often due to Crohn's disease. There are other diseases that can cause this too, like lymphoma and infectious processes. Hopefully a biopsy will be helpful in determining the cause.

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Response by:

Janice Frederick Rafferty, MD Janice Frederick Rafferty, MD
Professor of Surgery
Chief of Colorectal Surgery Division
College of Medicine
University of Cincinnati