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Pharmacy and Medications

Information on the Nebivolol

11/25/2008

Question:

My wife 44 years old. She is hypertensive and is taking Tenormin 100 and Losartan 100 with MVP on Echo. All other parameters are OK. EF is 70%. Recently, she was having breathlessness ans she consulted chest physician who advised PFT which says "mild restriction with obstruction: mild reversibility." Her MVV is 23% ESA Obs Low VC. Doctor has advised to change Tenormin 100 to Nebivolol 5 mg. In fact she is taking Tenormin 100 since 5 years. I need your guidance about the new drug. This is not treatment recommendations but guidance.

Answer:

Nebivolol is a new cardio-selective beta blocker that lowers blood pressure and/or heart rate while having minimal effects on respiratory function. The most common side effect is dizziness/lightheadedness or headache, but these should go away after your wife gets used to this medication.

If these symptoms persist, she should contact her physician. She should not stop taking the nebivolol abruptly because this can raise her blood pressure. Make sure she continues to check her blood pressure regularly to ensure that the nebivolol is helping with her condition.

Submitted by Arnold Coleman, PharmD Candidate, The Ohio State University College of Pharmacy

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Response by:

The Ohio State University Carmen M. Hadley, RPh, CSPI
Clinical Instructor
Central Ohio Poison Center
Nationwide Children’s Hospital
College of Pharmacy
The Ohio State University