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COPD (Chronic Obstructive Pulmonary Disease)

COPD

11/10/2008

Question:

What are the potential changes in an ABG for COPD`s in their chronic maintance stage,acute exacerbation anf their end stage

Answer:

Generally the more advanced the COPD, the more likely the oxygen (O2) to decrease. With very advanced disease (lung function less than 40% of predicted), the carbon dioxide (CO2) may increase. However, it is possible for some individuals with very severe COPD to maintain a normal O2 and CO2 (if they are in a stable, "maintenance" state). With exacerbations, the O2 may decrease further and the CO2 level may increase to life threatening levels. Generally the higher the CO2 level, the more acidotic the blood is.

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Response by:

Mahasti   Rittinger, RRT Mahasti Rittinger, RRT
Clinical Program Manager of Pulmonary, Allergy, Critical Care & Sleep
College of Medicine
The Ohio State University