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Pharmacy and Medications

Could This Combination of Medicines Cause Kidney Failure?

11/19/2008

Question:

My father has been taking these medicines: Cephalexin 500mg, Lyrica 100mg, Lisinopril1 2.5mg, Nabumetone 500mg, Nortriptyline 50mg, Metflormin500mg, and Kadian30mg. He is in the hospital now with kidney failure on a machine they have ran many test to rule out everything possible. I keep telling them it is a combination of all these drugs. By the way, he is allergic to Penicillan,and Morphine.

Answer:

Without knowing your father’s specific medical profile, I cannot offer much advice with regard to his medications. If he is on hemodialysis for his kidney failure, I can recommend that metformin may not be the best medication for controlling his diabetes.

You should discuss any concerns you have with his primary care physician because he or she will know his medical history and will be able to make a better recommendation for him.

Submitted by Arnold Coleman, PharmD Candidate, The Ohio State University College of Pharmacy

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Response by:

The Ohio State University Carmen M. Hadley, RPh, CSPI
Clinical Instructor
Central Ohio Poison Center
Nationwide Children’s Hospital
College of Pharmacy
The Ohio State University