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NetWellness provides the highest quality health information and education services created and evaluated by faculty of our partner universities.
Thursday, February 9, 2012
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Pharmacy and Medications |
Is Paxil More Effective Than Lexapro for Helping with Premature Ejaculation?12/23/2008 |
Which is most effective for premature ejaculation: Paxil or Lexapro? In fact I am taking Lexapro 10 for anxiety but as of late I have a problem of premature ejaculation. Doctor advised to stop Lexapro 10 and start Paxil 20 before coitus. Can you guide me as to the better effictive drug for premature ejaculation Paxil 20 or Lexapro 10?
Thank you for visiting NetWellness. There are not any head-to-head data (studies that compare one agent to another agent) comparing Escitalopram and Paroxetine for the treatment of PE. In placebo (inactive drug vs active drug) controlled trial conduct by Safarinejad MR. in the Journal of Clinical Psychopharmacology (J Clin Psychopharmacol. 2007 Oct;27(5):444-50.) concluded the drug to be effective, but further studies were indicated for final conclusions.There are many published articles on the use of paroxetine and its use in PE. Objective results are usually seen after two weeks treatment with paroxetine, with prolongation to ejaculation time ranging between 6 to 10 minutes compared to less than 1 minute at baseline. Significant subjective changes included increased sexual desire, partner satisfaction, and decreased anxiety. However, over 90% will relapse to baseline functional status within two to three weeks after discontinuing medication.
On-demand treatment with SSRIs generally exert much less ejaculation delay than daily SSRI treatment. (Ludovico et al, 1996; McMahon & Touma, 1999; Waldinger MD et al, 2007).
On this site, we try to answer general questions about medications but cannot diagnose or recommend treatment. I encourage you to discuss these treatment options at further length with your prescriber.
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Sarah Hudson-DiSalle, PharmD, RPh Specialty Practice Pharmacist Department of Pharmacy The Ohio State University Medical Center The Ohio State University |