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Prostate Cancer

Post Prostate Surgery PSA Level

02/05/2009

Question:

My father-in-law had radical prostate surgery 11 years ago but has continued to receive various treatments and has been symptom free. Two months ago he had a PSA reading of 4 and just today he learned his PSA had doubled to 8. He was told to come back in a month for another PSA test. What is the most likely explanation for this? At this stage, what is the most likely prognosis and treatment?

Answer:

He needs to be evaluated for likely recurrent disease. He will probably need a bone scan and maybe a pelvic CT scan. He should discuss with his doctor the possible role of adjuvant radiation and/or hormone therapy if appropriate for his case.

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Response by:

Lee E Ponsky, MD Lee E Ponsky, MD
Associate Professor of Urology
School of Medicine
Case Western Reserve University