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Trying to conceive



Please advise if I can combine metformin, duphaston and folic acid. I am 30 years old and trying to conceive for 1 year.

Thanks in advance for your help.


Metformin is an anti-diabetic drug often used in women with polycystic ovaries to help them ovulate. Duphaston is a progestin used to start a menstrual period in women who have not ovulated. Folic acid is a vitamin (Vitamin B9) taking during early pregnancy to decrease the risk of birth defects, including one known as spinal bifida. These medications are not known to interact. When you are taking more than one medication (especially if prescribed by more than one physician), it is a good idea to ask your physician if they interact.

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Response by:

William W Hurd, MD William W Hurd, MD
Professor of Reproductive Biology
School of Medicine
Case Western Reserve University