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Pharmacy and Medications

Is it Safe to Vicodin and Amitriptyline on the Same Day?



Is it ok to take Amitriptyline (100 mg before bedtime) after taking Vicodin earlier in the day?


There is no problem with taking amitriptyline and hydrocodone/acetaminophen (Vicodin).

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Response by:

Michael  Ganio, PharmD Michael Ganio, PharmD
Clinical Applications Pharmacist
Wexner Medical Center
The Ohio State University