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Eye and Vision Care




my 3year old son has phpv and i want to know the latestnews about the treatment and etiology in the world it is anteroposterior and is blind


PHPV is a failure of the eye to develop normally. During development, there is an artery that supplies the lens in the front of the eye. This artery usually breaks down and goes away as development continues. The artery breaks down so that there is a clear pathway for light to get to the back of the eye.

In some individuals, remnants of the artery remain. For most people these remnants are harmless and have no effect on an individual's vision; however, if significant portions of the artery remain it can have a very detrimental affect on vision. The lens that is normally clear may become cloudy (cataract) and the vitreous (gel-like substance inside the eye) is also cloudy instead of being clear.

Unfortunately, many complications can arise from PHPV and many times vision remains poor. Some options are cataract removal, vitrectomy removal, and sometimes the insertion of an artificial lens in place of the cloudy natural lens.

In a study performed in Jerusalem, with the combined form (or anteroposterior form) the patients had the least optimistic visual acuity following surgery, however one patient did get better than 20/60 visual acuity (3.3%). Nearly half of patients with the combined form ended up with no light perception (total blindness).

The best thing you can do is find a pediatric ophthalmologist who can inform you of the best surgical options and provide a better idea of surgical outcomes.

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Response by:

Aaron  Zimmerman, OD, MS Aaron Zimmerman, OD, MS
Clinical Associate Professor of Optometry
College of Optometry
The Ohio State University