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Arthritis and Rheumatism

Simponi

04/30/2009

Question:

I have not responded to very good to the biologics. I am allergic to Humira, so my doctor will not give me Remicade. What can you tell me about Simponi? Where I am allergic to Humira could I be allergic to Simponi?

Answer:

Your comment suggests that your physician is trying to avoid biologic medications that are known as anti-TNF-alpha agents. Etanercept (Enbrel), infliximab (Remicade), adalimumab (Humira), and golimumab (Simponi) are all anti-TNF-alpha agents.

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Response by:

Raymond  Hong, MD, MBA, FACR Raymond Hong, MD, MBA, FACR
Formerly, Assistant Professor of Medicine
School of Medicine
Case Western Reserve University