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Pharmacy and Medications

Combining Meds in an IM



Can you combine IM benadryl, haldol and ativan into one syringe?


No. Bendadryl (diphenhydramine) and haldol (haloperidol) are incompatible in the same syringe- a white precipitate will form. Benadryl and ativan (lorazepam) have not been tested for compatibility, so it would not be responsible to mix them.


Haldol and ativan may be combined in the same syringe.


Submitted by Matthew Chamberlain, PharmD Candidate

Midwestern University College of Pharmacy.

Reference: Trissel’s 2 Clinical Pharmaceutics Database (Parenteral Compatibility)- subscription required

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Response by:

Carmen M Hadley, RPh, CSPI
Former Clinical Instructor
College of Pharmacy
The Ohio State University