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Cone biopsy and LEEP



does a cone biopsy conization cause infertility?


Cone biopsy and LEEP (Loop Electrosurgical Excision Procedure) are both methods to evaluate and remove precancerous or cancerous lesions of the cervix. Many physicians use these procedures interchangably.

Each are proposed causes of "cervical factor" infertility. The removal of a portion of the cervix can cause narrowing/closure of the cervix or change the normal cervical mucus. It is believed that these conditions can cause difficulty for sperm to ascend into the uterus and fertilize the egg.

Fortunately, this uncommon cause of infertility can be remedied by intrauterine insemination (IUI) where purified sperm are injected through the cervix into the uterus.

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Response by:

Arthur T Ollendorff, MD Arthur T Ollendorff, MD
Associate Professor of Obstetrics and Gynecology
College of Medicine
University of Cincinnati