Pharmacy and Medications |
Progesterone Dose During Pregnancy02/03/2011 |
Is 200mg of progesterone vaginally 3 times daily an excessive dose for maintenance of pregnancy? Would it matter if the person had factor v leiden?
This is a difficult one. The American College of Obstetrics and Gynecology endorses a protocol of progesterone 100 mg vaginal suppositories once daily or progesterone 250 mg IM once weekly in women with a history of preterm delivery. Your condition may require a higher dosage. You should ask your doctor if he/she has a primary reference for the dose he/she is using. Perhaps this high dose is just for a short period of time, like a loading dose, and the plan is to lower it to once daily at a later date.
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Debra K Gardner, PhamD Former Assistant Clinical Professor of Pharmacy College Business Office Internal Resource Pool-Allied at OSU Medical Center Wexner Medical Center The Ohio State University |