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Wednesday, June 19, 2013
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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Wednesday, June 19, 2013
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Pharmacy and Medications |
Dosage Equivalencies03/10/2011 |
What is the equivalent dose of dessicated porcine thyroid to replace 100mcg of Levoxyl? The dessicated thyroid comes in milligrams so it appears that the numbers don`t translate directly.
The reason that the numbers do not translate directly is that the desiccated thyroid (ArmourTM Thyroid) product is a natural product derived from porcine thyroid containing both T4 (levothyroxine) and T3 (liothyroxine) in a ratio of 4.22:1. Levoxyl® on the other hand is a synthetic compound containing only levothyroxine (T4).
The general conversion used for switching from Levoxyl® to desiccated thyroid is generally 25mcgs of Levoxyl® for every 15mgs (1/4 grains) of desiccated thyroid. So when switching from 100mg of Levoxyl®, the equivalent dose of desiccated thyroid would be 60mgs (1 grain).1
1. Drug facts and Comparisons:2009 Edition. Wolters Kluwer Health; 2009:486-95
Answer submitted by Charles Skluzacek, Ohio State University-College of Pharmacy, PharmD Candidate, Class of 2011
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David Baker, PharmD, DABAT Formerly, Clinical Assistant Professor of Pharmacy College of Medicine The Ohio State University |
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