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Breast Cancer

Effect of Hormone Therapy on Breast Lumps



Can hormone theropy (estradiol and medroxyprogesterone) cause or contribute to a lump in the breast that was not cancerous before taking the hormones?


Yes, just like changes that occur in the breasts with your menstrual cycles, estrogens that are given as a medication can cause breast swelling and cysts. All lumps that are changing should be checked by your doctor, even if they were not cancerous earlier.

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Response by:

Paula  Silverman, MD Paula Silverman, MD
Associate Professor of Medicine
School of Medicine
Case Western Reserve University