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Saturday, March 8, 2014
Could polycystic kidney disease develop later on in life? Would the following "clinical impressions" warrant seeing a nephrologist: kideny stone, UTI, diverticulitis, high blood pressure, and sliding hiatal hernia.
Yes, polycystic kidney disease (PKD) does typically develop later in life. In this disease, a person is born with normal kidneys, but gradually develops cysts in them; the cysts are usually evident by the time the person is in their 20's, but the disease is often not diagnosed until age 30-50's. There are other signs that accompany this disease, including high blood pressure, cysts in other organs (especially the liver), blood in the urine, kidney stones, a heart valve disorder called mitral valve prolapse, colonic diverticulosis, and hernias (especially inguinal, but not hiatal).
Anyone who has PKD has a 50% chance of passing it on to each of their children.
I hope that this information answers your questions; but if not, please feel free to write back with more specific questions.
Mildred Lam, MD
Associate Professor of Medicine
School of Medicine
Case Western Reserve University